Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase

J Med Chem. 1998 Jul 30;41(16):2934-8. doi: 10.1021/jm980264k.
No abstract available

MeSH terms

  • Administration, Oral
  • Animals
  • Blood Glucose / metabolism
  • Cell Line
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / prevention & control
  • Enzyme Inhibitors / administration & dosage
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Glycogen / metabolism
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / chemical synthesis*
  • Hypoglycemic Agents / chemistry
  • Hypoglycemic Agents / pharmacology
  • Indoles / administration & dosage
  • Indoles / chemical synthesis*
  • Indoles / chemistry
  • Indoles / pharmacology
  • Liver / cytology
  • Liver / enzymology*
  • Liver / metabolism
  • Mice
  • Mice, Obese
  • Phosphorylases / antagonists & inhibitors*
  • Recombinant Proteins / antagonists & inhibitors
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • Blood Glucose
  • Enzyme Inhibitors
  • Hypoglycemic Agents
  • Indoles
  • Recombinant Proteins
  • Glycogen
  • Phosphorylases